The Ben-Shalom Lab aims to decipher the mechanisms of neuronal excitability and network function to better understand and treat neurodevelopmental conditions such as autism, epilepsy, and developmental delays. The lab combines computational modeling and advanced electrophysiological techniques to study neuronal function in a variety of model systems.

Recent work includes:

• Characterizing neurodevelopmental conditions using high-density microelectrode arrays (MEA)
• Utilizing primary neurons derived from genetic mouse models of neurological disease
• Investigating functional properties of patient-derived iPSCs and organoids
• Developing deep learning algorithms to predict neuronal properties from electrophysiological data
• Using empirical data to create computational models of channels, neurons, and networks

The lab is dedicated to advancing our understanding of brain function and developing new approaches for diagnosing and treating neurological conditions.